The term
as it appears in Equation 10
(and various others) can be further optimised if a theoretical OTF is used.
An experimentally obtained OTF
requires its Fourier transform to be
calculated in order for it to be convoluted with the smoothing function
4, this requires both memory and time. However, if a theoretical equation is
obtained for
, then the entire term
may
be evaluated theoretically. This will give an equation that can be used in the
algorithm, in order to deconvolute Equation 10.
Thus, a substantial amount of time and memory can be saved by using a theoretically
computed OTF. Refer to Section 2.2 for details of what
OTF was used.